Frequency of Vitamin D Deficiency among Patients with Newly Diagnosed Chronic Kidney Disease

Najamuddin ., Ahmad Zeb Khan, Mufti Baleegh-ur-Raheem ., Mahmood ., Syed Munib, Mazharul Haq, Waqas Sardar


Background: Chronic Kidney Disease is a condition which is frequently caused by long standing diabetes, hypertension, renal
calculus disease and glomerulonephritis. The term End Stage Renal Disease usually means the final stage of Chronic Kidney
Disease with a decline in Glomerular Filtration Rate below 15 ml/min. Recently a great deal of interest has been created world over in the correction of native vitamin D levels in CKD patients and its ability to slow the progression of CKD patients.
Objective: To determine the frequency of vitamin D deficiency among patients with newly diagnoses of chronic kidney disease.
Material & Methods: This descriptive and cross-sectional study was conducted at Department of Nephrology, Institute of Kidney
Disease (IKD), Peshawar. It was conducted for the period of 06 months from 01 May, 2018 to 30 October, 2018. The sample size was 190 patients and consecutive non-probability sampling was carried out. All patients newly diagnosed CKD in the age range of 18-60 years and both gender were included, while all the patients having CKD 5 (HD dependent and non-HD dependent) were excluded. Patients already diagnosed with osteomalacia and vitamin D deficiency, patients having hepatic diseases (as diagnosed by specific investigations or medical records) and patients on vitamin D supplementation were also excluded from this study. Vitamin D deficiency was considered positive if the serum vitamin D level was less than 20ng/ml. All the data was analysed in SPSS 22.
Results: In this study, the mean age was 40.6 years with standard deviation ± 14.15. 65% patients were male and 35% were female. Forty percent patients had vitamin D deficiency.
Conclusion: Our study shows that the frequency of vitamin D deficiency is 40% among patients with newly diagnoses of CKD at our center.


Vitamin D deficiency, chronic kidney disease

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