Spectrum of Pseudomonas Aeruginosa Sensitivity in Chronic Otitis Media

Syed Maisam Ali, Junaid Hussain Mahesar, Junaid Shahzad, Akhtar Zaman, Wahhi -ud-Din Shinwari, Tahira Sajid, Sabir Khan Khattak


Background: Chronic otitis media is perforation of tympanic membrane with infection. It is mostly seen in underdeveloped
countries. Culture and sensitivity reports show that the major pathogens responsible for chronic otitis media are pseudomonas
aeruginosa and staphylococcus aureus.
Objective: To ascertain the sensitivity of Pseudomonas Aeruginosa in chronic otitis media which will help in the selection of
antibiotics in resistant cases of chronic otitis media.
Materials and Method: This prospective cross sectional study including 150 patients was carried at PNS Shifa Hospital, Karachi
from 20/04/2017 to 05/01/2018.Pus sample/swab was collected via pre-packed sterile cotton sticks for bacteriology and sent to
consultant microbiologist for culture and sensitivity. Laboratory reports of the bacterial spectrum and their sensitivity to antibiotics
were reviewed and data entered in the proforma was analyzed.
Results: After processing 36.6% pseudomonas aeruginosa infections were sensitive to Piperacillin + tazobactam while 60.98%
sensitive to ciprofloxacin, 34.15% to Amikacin and 31.71% only to Ceftriaxone. There is no significant correlation of pseudomonas
aeruginosa with duration of disease, residential status, education and socioeconomic status while significant correlation was found
with three antibiotics except ceftriaxone sodium.
Conclusion: In chronic otitis media the commonest agent being implicated is Pseudomonas aeruginosa. Ciprofloxacin, Amikacin
and pipercillin+tazobectum were found to be the most sensitive antibiotic agents against Pseudomonas aeruginosa.


Chronic otitis media, Microbiology in otitis media, Antibiotic sensitivity.

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