Frequency of Carcinoma Prostate in Patients presenting with Clinically Benign Enlarged Prostate

Fazli Akbar, Anwar ul Haq, Nizam ud din, Mohammad Hussain, Zia ur Rehman, Amir Amanullah

Abstract


Background: Benign Prostatic hyperplasia is one of the commonest physiological ageing process of males. Among these, there are
chances of conversion of this benign condition into malignancy. Initially benign prostatic hyperplasia was tried to be controlled with
medication. Then came the era of open surgery in the form of Trans-vesical prostatectomy and now-a-days minimally invasive technique
of trans-urethral prostatectomy is on the surge. With the passage of time, there is increasing trend in performing histo-pathology of any
tissue taken out from the body and this has resulted in very fruitful results.
Objective: To determine the frequency of carcinoma prostate in those patients who were clinically suspected as having bening enlarged
prostate.
Material and Methods: This study was conducted in Surgical units and Urology unit of Saidu Group of Teaching Hospitals, Swat from
2013 to 2015. A total of 200 patients were included in the study. An exclusion criteria was made so as to exclude confirm cases of
carcinoma prostate from the study. After performing trans-vesical and trans-urethral prostatectomy, the specimens were sent for histopathology.
Results: 200 patients were selected for the study who were clinically assigned as having benign prostatic hyperplasia according to our
inclusion criteria. Out of these 200 subjects, 32 (16%) came out to be having carcinoma prostate while 168 (84%) patients retained the
original clinical diagnosis upon histo-pathology.
Conclusion: Rather than assigning a patient as having benign enlarged prostate on clinical grounds, it is better to perform histopathology
because there is a vast difference of management plan of a benign condition as compared to a malignant condition.

Keywords


Prostatitis, Benign prostatic hyperplasia, prostatic carcinoma, Digital rectal examination, International prostate symptoms score, Trans-vesical prostatectomy, Prostate specific antigen, Histo-pathology.

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