Effectiveness of Ciprofloxacin and Levofloxacin in treatment of Pseudomonas Aeruginosa infection

Imtiaz Ahmad, Wasil Khan, Aleem ur Rashid, Samiullah ,, Abdul Ahad, Aminullah ,, S. M. Naeem

Abstract


Background: Pseudomonas aeruginosa is the most troublesome and feared pathogen in medical field. It is the sixth most
common cause of hospital-acquired infections and the cause of ventilator-associated pneumonia. The most common multidrugresistant
gram-negative pathogen in Ventilated Assisted Patient. In our study in 100 patients culture and sensitivity report only 46%
were sensitive to oral treatment while 54% of the pseudomonas were resistant to ciprofloxacin and 34% sensitive and 66%
resistant to levofloxacin.
Objective: To find out resistance of pseudomonas to oral medication.
Material and Methods: A cross-sectional study, conducted in Saidu Group of Teaching Hospital from January 2018 to July 2019. ).
100 patient samples (tracheal aspirate, bronchial washing, sputum, pus, urine and blood) were cultured for pseudomonas and its
sensitivity to oral medication ciprofloxacin and levofloxacin was recorded.
Results: Sensitivity to 46% were samples was observed to oral treatment while 54% of the pseudomonas were resistant to
ciprofloxacin and 34% sensitive and 66% resistant to levofloxacin respectively.
Conclusion: It was found that 54% pseudomonas were resistant to Ciprofloxacin and 66% resistant to levofloxacin. So we should
always consider for combination therapy.

Keywords


Pseudomonas, oral medication, culture and sensitivity, resistance

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