Effectiveness of Ciprofloxacin and Levofloxacin in treatment of Pseudomonas Aeruginosa infection

  • Imtiaz Ahmad
  • Wasil Khan
  • Aleem ur Rashid
  • Samiullah ,
  • Abdul Ahad
  • Aminullah ,
  • S. M. Naeem
Keywords: Pseudomonas, oral medication, culture and sensitivity, resistance

Abstract

Background: Pseudomonas aeruginosa is the most troublesome and feared pathogen in medical field. It is the sixth mostcommon cause of hospital-acquired infections and the cause of ventilator-associated pneumonia. The most common multidrugresistantgram-negative pathogen in Ventilated Assisted Patient. In our study in 100 patients culture and sensitivity report only 46%were sensitive to oral treatment while 54% of the pseudomonas were resistant to ciprofloxacin and 34% sensitive and 66%resistant to levofloxacin.Objective: To find out resistance of pseudomonas to oral medication.Material and Methods: A cross-sectional study, conducted in Saidu Group of Teaching Hospital from January 2018 to July 2019. ).100 patient samples (tracheal aspirate, bronchial washing, sputum, pus, urine and blood) were cultured for pseudomonas and itssensitivity to oral medication ciprofloxacin and levofloxacin was recorded.Results: Sensitivity to 46% were samples was observed to oral treatment while 54% of the pseudomonas were resistant tociprofloxacin and 34% sensitive and 66% resistant to levofloxacin respectively.Conclusion: It was found that 54% pseudomonas were resistant to Ciprofloxacin and 66% resistant to levofloxacin. So we shouldalways consider for combination therapy.
Published
2020-06-09
How to Cite
1.
Ahmad I, Khan W, Rashid A ur, , S, Ahad A, , A, Naeem SM. Effectiveness of Ciprofloxacin and Levofloxacin in treatment of Pseudomonas Aeruginosa infection. J Saidu Med Coll Swat [Internet]. 2020Jun.9 [cited 2022Sep.28];10(1). Available from: http://jsmc.pk/index.php/jsmc/article/view/294

Most read articles by the same author(s)