Comparison of Fetal Outcome in Pre-eclampsia with Hyperuricemia and Normal Uricemic Patients
Keywords: Pre-eclampsia, hyperuricemia, fetal outcome.
AbstractBackground: Pre-eclampsia with hyperuricemia is a complication of pregnancy associated with fetal mortality and morbidity. The main complications are preterm delivery, low birth weight and intrauterine demise of the fetus along with higher rate of cesarean section.Objective: To compare fetal outcome in pre-eclampsia with hyperuricemia and with normal uricemic controlMaterial and Methods: Study was conducted at department of the Gynecology “B” Hayatabad Medical Complex Peshawar from 1st August 2016 to 31st July 2017. Patients with pre-eclampsia were divided in two groups “A” and “B”. In group “A” patients with serum uric acid level > 6mg/dl and in group “B” patients with uric acid level of < 6mg/dl were included. The low birth weight, preterm birth, rate of cesarean sections and intrauterine death were observed in the two groups. Results: Among the 60 patients with hyperuricemia 34 (56.66%) babies born with low birth weight, rate of cesarean section was 53.33% (32), pre-term delivery 48.33% (29) and intrauterine deaths 6.66% (4). While in 60 patients with normal uricemic control 7 (11.66%) babies born with low birth weight, rate of cesarean section was 13 (21.66%), pre-term delivery 16 (26.66%) and intrauterine deaths 0 (0.00%).Conclusion: Increased uric acid level is a poor predictor for fetal outcome in terms of low birth weight, preterm birth, rate of cesarean sections and intrauterine death.