SIGNIFICANCE OF WIDAL TEST IN THE DIAGNOSIS OF TYPHOID FEVER
DOI:
https://doi.org/10.52206/jsmc.2012.2.2.178-181Abstract
Objective: The aim of our study was to determine the role of Widal test with appropriate titters in diagnosis
of Enteric fever in an endemic area of District Swat.
Materials and Methods: The study was conducted in Saidu Teaching Hospital, Saidu Sharif between
October 2010 and April 2012. Patients more than 15 years old and more than seven days of fever were
included in this study.Widal test was also done on 200 normal individuals, 197 non-typhoidal fevers and 175
bacteriologically proven cases of typhoid.
Results: Of 200 normal individuals, 2% had an H agglutinin titre of 1/160 and 5% had an O agglutinin titre
of 1/160. H and/or 0 agglutinin titre of 1/320 or more was observed in 93-97% of typhoid cases and in only
3% of patients with non-typhoidal fever. Of the sera from typhoid cases which gave a significant Widal
reaction, the majority (79.9%) showed increases in both H and 0 agglutinins and 51 of 234 (21.8%) of these
sera were collected in the first week of illness.
Conclusion : Based on these data it is evident that an H and/or 0 agglutinin titre of: 1/320 or more should be
considered significant and indicative of typhoid fever.
Key words; Widal test, Gram negative bacterium, agglutinin titres
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