Fate of Emphysematous Pyelonephritis: A Single Center Study

Authors

  • Muhammad Naeem Urology Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar Pakistan
  • Riaz Ahmad Khan Urology Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar Pakistan.
  • Ghaffar Shah Urology Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar Pakistan.
  • Asad Shamsher Urology Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar Pakistan.
  • Bakhtawar Gul Urology Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar Pakistan

DOI:

https://doi.org/10.52206/jsmc.2021.11.4.677

Abstract

Background: Emphysematous Pyelonephritis (EPN) is a Urological emergency. It is a gas forming infection of the renal
parenchyma and also involves the perirenal fat. It affects persons having Diabetes Mellitusspecifically females.
Objectives: To present clinical features, and compare abnormal laboratory investigations among poor and good outcome in
patients affected by emphysematous pyelonephritis.
Materials and methods: This retrospective study was conducted in Institute of Kidney Diseases Hayatabad Peshawar on records
of 50 patients affected by EPN. Patients having age from 35 to 85 years, clinical feature of upper urinary tract infections, and gas
accumulation in renal parenchyma seen on computed tomography (CT) scan were included in the study. Age, sex, control of
glucose status and abnormal laboratory investigations were recorded. Outcome was measured as poor or good. Data analysis
was done in SPSS version 22.
Results: The mean age was 63.1±11.48 years and 62% were females. The clinical features in patients with EPN was fever (n=37,
74%) Flank, abdomen, or back pain (n=34, 68%). Urine analysis showed that pyuria was common (n=35, 70%) followed by severe
proteinuria (n=31, 62%). Macrohematuria was found in 19(38%), thrombocytopenia in 24(48%) and leukocytosis in 28(56%)
patients. In 35(70%) patients HbA1C was > 8% of which 6(12%) died (P=.021). In 32(64%) the outcome was good.
Conclusion: Emphysematous Pyelonephritis affects females more than males. Most common abnormal laboratory findings are
leukocytosis, thrombocytopenia and HbAIC > 8%. EPN is a fatal disease so quick management is required.
Keywords: Emphysematous Pyelonephritis, Diabetes Mellitus, Pyuria, Proteinuria, Macrohematuria.

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How to Cite

1.
Muhammad Naeem, Riaz Ahmad Khan, Ghaffar Shah, Asad Shamsher, Bakhtawar Gul. Fate of Emphysematous Pyelonephritis: A Single Center Study. J Saidu Med Coll Swat [Internet]. 2021 Dec. 2 [cited 2022 Nov. 30];11(4):191-5. Available from: http://jsmc.pk/index.php/jsmc/article/view/677

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