Evaluation of Altered Oral Changes in Covid-19 PCR Positive Cases- A Cross Sectional Study
DOI:
https://doi.org/10.52206/jsmc.2024.14.4.956Abstract
Background: The Coronavirus Disease caused by SARS-CoV-2 had rapid and worldwide transmission, which resulted in a significant number of fatalities. The virus is known to spread through close contact via exposure to infected droplets and aerosols, and it can infect cells in the upper respiratory tract. However, it was unclear whether the virus directly infects the tissues of the oral cavity and alter oral physiology, resulting in oral symptoms in many COVID-19 patients.
Objective: The present study was performed to evaluate the altered oral changes in covid-19 PCR positive cases.
Materials and Methods: The cross-sectional study was carried out in 211 PCR confirmed patients of SARS-CoV-2. Data was collected using a digital questionnaire for each patient. Saliva was collected through “passive drool” procedure. Both direct samples and extracted RNA were used for qRT-PCR targeting the conserved region of the SARS-CoV-2 genome, the N and ORF1ab genes. Descriptive statistics were computed
Results: There were 211 confirmed patients of COVID-19, out of which 146 (69%) were male and 65 (31%) were female. Regarding oral symptoms in COVID-19 positive patients, Xerostomia and Amblygeustia were commonly reported, with 87% and 90.5% of patients experiencing these symptoms, respectively. Acute parotitis was also reported by 49(23%) patients, indicating that it may be a potential oral symptom of COVID-19.
Conclusion: This study concludes that xerostomia (87%) and amblygeustia(90.5%) are common oral symptoms in SARS-CoV-2 positive patients, and acute parotitis(23%) is also a potential oral symptom.
Keywords: Amblygeustia, COVID-19, Oral, Parotitis, Xerostomia.
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