Experience of lodopovidone Pleurodesis at A Tertiary Care Hospital in Peshawar
DOI:
https://doi.org/10.52206/jsmc.2021.11.3.644Abstract
Background: Chemical pleurodesis is used for the management of malignant /recurrent pleural effusion and pneumothorax.
Malignant pleural effusion is diagnosed on histopathology or malignant cells in pleural fluid. Pneumothorax is diagnosed by chest
radiograph. Pleurodesis can be performed surgically or by using medical agents. Various pleurodesis agents have been used e.g.
Tetracycline.Bleomycin. Talc and lodopovidone with different success and complications rates.
Objective: This study was conducted to know the efficacy and safety of lodopovidone as pleurodesis agent in the
management of pleural effusion (malignant/recurrent) and recurrent pneumothorax.
Material and Methods: This was a descriptive study conducted at department of Pulmonology Lady Reading Hospital
Peshawar from February 2018 to May 2019.
Results:A Total of 213 patients were included in the study, among which 120 (56.3%) were males and 93 (43.6%) were
females. Age range was from 20 to 83 years. One hundred and thirty eight patients (74.8%) had malignant pleural effusion and
75 (35.2%) had recurrent pneumothorax. The success rate with lodopovidone pleurodesis was 85 % (181) as a whole with a
failure rate of 13 %( 28) in pleural effusion and 2 %( 4) in pneumothorax. Chest pain (65.7%) was the most common side effect
followed by fever (24.4%) and dyspnea (12.2%).No serious side effects were observed in this study.
Conclusion: lodopovidone is easily available, safer, cheaper and effective agent for chemical pleurodesis in pneumothorax,
malignant/recurrent pleural effusion.
Keywords: Pleurodesis, lodopovidone. Malignant, Pleural Effusion, Pneumothorax.
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