Lower Ureteric Stone Expulsion under the Effect of Alpha Blockers: A Clinical Trial over Alpha Blockers Efficacy

Abstract

Background: The ureters account for over 20% of urinary tract stones. The lifetime chance of having urinary calculi is between 5-12%, and men are more likely than women to develop them. There are a variety of minimally invasive interventional (ESWL and Ureteroscopy) and expectant options. However, the optimum therapy is mostly determined by the type and size of the stone, as well as the stone's location and the patient's demands. We do minimal invasive procedures like ureterostomy and ESWL to remove stone in ureter with some complications.

Objective: To determine the efficacy of alpha blockers in expulsion of lower ureteric stones less than 1cm.
Materials and Methods: Research was conducted in the Department of Urology, A total of 195 patients were included in this study. All patients were subjected to history taking and examination for suspected ureteric stone. Urine R/E and blood test was performed, which included serum urea and creatinine levels, as well as an x-ray KUB and ultrasound of the pelvis and abdomen by giving alpha blockers 0.4mg at night. Efficacy was measured after four week.
Results: Our study shows that among 195 patients, 127(65%) patients were in age 15-40 years and 68(35%) patients were in age 41-60 years. 119(61%) patients were male and 76(39%) patients were female. 88(45%) patients had stone size = 10 mm and 107(55%) patients had stone size >10mm. More over alpha blocker was effective in 115(59%) patients and was not effective in 80(41%) patients.
Key Words: efficacy, alpha blockers, expulsion, lowers ureteric stones.