Review of Feto-Maternal Outcome in Patients with Premature Rupture of Membranes at Term
DOI:
https://doi.org/10.52206/jsmc.2024.14.2.855Abstract
Background: Premature rupture of membranes complicates 5 to 10 % of the singleton pregnancies and is a major contributor of maternal morbidity and neonatal morbidity and mortality in terms of sepsis and prematurity, even in the today's era of antibiotics. Most of these complications can be prevented provided timely, targeted management is initiated.
Objectives: To provide a comprehensive understanding of the fetal and maternal outcome with premature rupture of membranes at term, for a better management.
Material and Methods: This descriptive Cross Sectional study was conducted in department of Obstetrics and Gynecology HMC, from 15th of September 2022 till 15th of February 2023. Random sampling method was adopted in this study and a total of 241 patients presented with spontaneous rupture of membranes after 37 weeks till 41 weeks. A detail history, physical and gynecological examination was performed, and all the information gathered from the patient by the doctors was then recorded on a pre-designed proforma.
Results: Out of 241 patients of PROM 60 cases of maternal and 145 cases of fetal complications were observed. As per maternal outcomes, 28(46.7%) patients had wound infection,16(26.6%) patients developed oligohydramnios, 07 (11.7%) patients were recorded with Puerperal Pyrexia secondary to endometritis, and 09 (15%) patients developed chorio-amnionitis. About 56% of the mothers had cesearen deliveries. As per fetal outcomes, 78(53.8%) cases were recorded with RDS, 35(24.1) with hyperbilirubinemia, 23 (16%) babies developed neonatal sepsis, and 09(6.2%) had necrotizing Enterocolitis.
Conclusion: Premature Rupture of Membrane at term has a risk of both fetal and maternal complications. Prolonging pregnancy as in conservative management adds to the fetal and maternal morbidity more in terms of sepsis. In this study, we concluded that conservative management to prolong pregnancy carry risk both for mother and baby and is recommended only under strict monitoring.
Keywords: Chorioamnionitis, Latency period, Maternal outcome, Perinatal outcome, Sepsis.
References
Sarkar M, Mondal T, Sarkar M. PROM and its maternal outcome: a retrospective study in a rural medical college of India. Intel J Reprod Contracept Obstet Gynecol 2021 Jun 1;10(6):23-80. DOI: https://dx.doi.org/10.18203/2320-1770.ijrcog20212179.
Wijaya D, Darusalam D. The Impact of Premature Rupture of Membranes (PROM) and Low Birth Weight (LBW) Infant Outcomes to the Survival Rate. Indonesia J Obstet Gyneco 2022 Apr 28:72-8. DOI: https://doi.org/10.32771/inajog.v10i2.1553
Shams A M, Amin N, Syed H. Effect of Mode of Delivery and Number of Parity on Abnormal Placental Location. Pak Armed Forces Med J 2022;72(2):489-492. DOI: https://doi.org/10.51253/pafmj.v72i2.4701
Zhuang L, Li ZK, Zhu YF. Latency period of PROM at term and the risk of neonatal infectious diseases. Sci Rep 2022:12,122-75. DOI: https://doi.org/10.1038/s41598-022-16593-6
Chandra SN, Pradeep MR. Maternal and Neonatal Outcomes and the Associated Risk Factors for Premature Rupture of Membranes. J South Asian Feder Obst Gynae 2020;12(6):402-40. DOI: https://doi.org/10.5005/jp-journals-10006-1836
Sharma SK, Dey M. Maternal and neonatal outcome in cases of premature rupture of membranes beyond 34 weeks of gestation. Int J Reprod Contracept Obstet Gynecol 2017;6(4):1302-05. DOI: https://doi.org/10.18203/2320-1770.ijrcog20171382
Kasliwal A, Kabra I, Yadav P. Maternal and fetal outcome in premature rupture of membrane. Indian J Obstet Gynecol Res 2021;8(3):328-333. DOI: https://doi.org/10.18231/j.ijogr.2021.069
Singh J, Kanti V, Verma V. Study of fetomaternal outcome in cases of premature rupture of membrane at tertiary care rural institute of Western Uttar Pradesh, India. Int J Reprod Contracept Obstet Gynecol 2020 Jan 1;9(1):78. DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20196000
Nagaria T, Diwan C, Jaiswal J. A study on feto-maternal outcome in patients with premature rupture of membranes. Int J Reprod Contracept Obstet Gynecol 2016 Dec 7;5(12):4123-7. DOI: http://dx.doi.org/10.18203/2320-1770.ijrcog20164181
Adhikary S, Tanira S, Sultana A, Wazed F, Chowdhury SB. Fetal outcome in Premature Rupture of Membrane A study conducted in a tertiary level hospital in Bangladesh. Mediscope 2020 Sep 29;7(2):108-12. DOI: https://doi.org/10.3329/mediscope.v7i2.49450
Savitha TS, Pruthvi S, Sudha CP, Nadig VS. A comparative study of feto-maternal outcome in expectant management versus active management in pre-labor rupture of membranes at term. Intel J Reprod Contracept Obstet Gynecol 2018 Jan 1;7(1):146-52. DOI: https://doi.org/10.18203/2320-1770.ijrcog20175836
Sudha R, Biradar P. Maternal and perinatal outcome in preterm premature rupture of membranes. Int J Reprod Contracept Obstet Gynecol 2023;12:706-10. DOI: https://doi.org/10.18203/2320-1770.ijrcog20230542
Singh N, Pattnaik L, Panda SR, Jena P, Panda J. Fetomaternal Outcomes in Women Affected with Preterm Premature Rupture of Membranes: An Observational Study from a Tertiary Care Center in Eastern India. Cureus 2022 May 31;14(5). DOI: https://doi.org/10.7759/cureus.25533
Zhuang L, Li ZK, Zhu YF, Ju R, Hua SD, Yu CZ, et al. Latency period of PROM at term and the risk of neonatal infectious diseases. Scientific Reports 2022 Jul 18;12(1):122-75. DOI: https://doi.org/10.1038/s41598-022-16593-6
Sarkar M. PROM and its maternal outcome: a retrospective study in a rural medical college of India. Int J Reprod Contracept Obstet Gynecol 2021 Jun 1;10(6):2379-2382. DOI: https://dx.doi.org/10.18203/2320-1770.ijrcog20212179
Alhubaishi LYA. Premature Rupture of Membrane and Neonatal Infection. Open Journal of Obstetrics and Gynecology 2019:9,1388-91. DOI: https://doi.org/10.4236/ojog.2019.910134
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