Deceased Donor Kidney Transplantation in Pakistan: An Underutilized Resource

Authors

  • Muhammad Abdul Mabood Khalil King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia
  • Nihal Mohammed Sadagah King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia
  • Jackson Tan Raja Isteri Pengiran Anak Saleha (RIPAS) Hospital, Brunei Darussalam
  • Ishida Hediki Tokyo Women's Medical University Hospital, Tokyo, Japan
  • Anwar Ul Haque Saidu Medical College/Saidu Group of Teaching Hospital, Swat, Pakistan https://orcid.org/0009-0003-1973-7993
  • Salem H Al-Qurashi King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia

DOI:

https://doi.org/10.52206/jsmc.2026.16.2.1461

Abstract

Pakistan has more than 241 million people [1]. But there isn’t a complete registry to show how many have chronic kidney disease (CKD). In 2024, only 28 centers shared their data, so the actual number of cases is probably higher [2]. Some studies estimate that about 24% to 25% of Pakistanis have CKD [3,4]. Based on these estimates, around 58-61 million Pakistanis have CKD. Treating CKD is very costly. Given the fragile economy, this is a major public health problem. Most people can’t get hemodialysis or peritoneal dialysis. Kidney transplants usually help people with CKD to live longer. Sporadic live kidney transplantation does happen in Pakistan. On the contrary, organ donation after death doesn’t happen much in Pakistan. As a result, deceased kidney transplantation is negligible in the country.

 

Pakistan puts just about 1% of its GDP into health care [5]. That means treatments like dialysis aren’t fully covered, and patients usually have to pay the costs themselves. Most big hospitals only do dialysis for emergencies. Very few centers provide long-term maintenance dialysis. In 2024–2025, the average person made around $1,824, but a year of dialysis can cost $13,510 [6,7]. Around 61% of people live in rural areas, where dialysis is even harder to access [8]. Even when people can get it, it’s rarely free.

 

Kidney transplants help people live longer and can really improve their quality of life [8,9]. The initial cost of transplant is high, but over time, it is lower than that of regular dialysis [10]. The first kidney transplant in Pakistan happened back in 1979, and since then, transplants from living donors have continued [11]. But it’s still very rare to get a kidney from a deceased donor. Kidneys donated after brain death (DBD) or donation after cardiac death (DCD) provide better survival than dialysis [12]. DBD is common in many countries, and DCD is also used in several places [13]. Due to advancements in pharmacotherapy and perfusion techniques, donated organs from deceased donors last longer than before [14]. For example, in the United States, a kidney from a deceased donor now lasts about 12 years, compared to just 8 years in the 1990s [15].

References

Pakistan Bureau of Statistics. Announcement of Results of 7th Population & Housing Census-2023. Islamabad: PBS; 2023. https://www.pbs.gov.pk/sites/default/files/population/2023/Press%20Release.pdf.

Pakistan Renal Registry 2024 Annual Report. Pakistan J Kidney Dis. 2025 Mar;9(1):1–22. https://doi.org/10.53778/pjkd91298

Khan A, Cheema MF, Fatima R, Cheema SS, Butt Z, Gillani S, et al. Prevalence of Chronic Kidney Disease in a High-Risk Population in Urban Lahore, Pakistan: A Cross-sectional Study. Cureus. 2024 Jun 27;16(6):e63296. https://doi.org/10.7759/cureus.63296

Saeed ZI, Hussain SA. Chronic kidney disease in Pakistan: an under-recognized public health problem. Kidney Int. 2012 Jun;81(11):1151. https://doi.org/10.1038/ki.2012.47

Government of Pakistan, Finance Division. Pakistan Economic Survey 2022–23: Health and Nutrition. Islamabad: Finance Division; 2023. https://www.finance.gov.pk/survey/11_health

Government of Pakistan, Finance Division. Pakistan Economic Survey 2024–25: Chapter 25 – Highlights. Islamabad: Finance Division; 2025. https://www.finance.gov.pk/survey/chapter_25/Highlights.pdf

Yeung E, Bello AK, Levin A, Lunney M, Osman MA, Ye F, et al Current Status of Health Systems Financing and Oversight for End-Stage Kidney Disease Care: a Cross-Sectional Global Survey. BMJ Open (2021) 11(7):e047245. https://doi.org/10.1136/bmjopen-2020-047245

Pakistan Bureau of Statistics. 7th Population & Housing Census 2023 (First Ever Digital Census): National Census Report. Islamabad: Pakistan Bureau of Statistics; 2023. https://www.pbs.gov.pk/wp-content/uploads/2020/07/ National-Census-Report-2023.pdf

de Boer SE, Knobbe TJ, Kremer D, van Munster BC, Nieuwenhuijs-Moeke GJ, Pol RA, et al. Kidney Transplantation Improves Health-Related Quality of Life in Older Recipients. Transpl Int. 2024 Apr 15;37:12071. https://doi.org/10.3389/ti.2024.12071

Laupacis A, Keown P, Pus N, Krueger H, Ferguson B, Wong C, et al. A study of the quality of life and cost-utility of renal transplantation. Kidney Int. 1996 Jul;50(1):235-42. https://doi.org/10.1038/ki.1996.307

Rizvi SA, Anwar Naqvi SA. Renal replacement therapy in pakistan. Saudi J Kidney Dis Transpl. 1996 Oct-Dec;7(4):404-8.

Strohmaier S, Wallisch C, Kammer M, Geroldinger A, Heinze G, Oberbauer R, et al. Survival Benefit of First Single-Organ Deceased Donor Kidney Transplantation Compared With Long-term Dialysis Across Ages in Transplant-Eligible Patients With Kidney Failure. JAMA Netw Open. 2022 Oct 3;5(10):e2234971. https://doi.org/10.1001/jamanetworkopen.2022.34971

Rijkse E, Ceuppens S, Qi H, IJzermans JNM, Hesselink DA, Minnee RC. Implementation of donation after circulatory death kidney transplantation can safely enlarge the donor pool: A systematic review and meta-analysis. Int J Surg. 2021 Aug;92:106021. https://doi.org/10.1016/j.ijsu.2021.106021

Hasjim BJ, Sanders JM, Alexander M, Redfield RR 3rd, Ichii H. Perfusion Techniques in Kidney Allograft Preservation to Reduce Ischemic Reperfusion Injury: A Systematic Review and Meta-Analysis. Antioxidants (Basel). 2024 May 24;13(6):642. https://doi.org/10.3390/antiox13060642

Poggio ED, Augustine JJ, Arrigain S, Brennan DC, Schold JD. Long-term kidney transplant graft survival-Making progress when most needed. Am J Transplant. 2021 Aug;21(8):2824-2832. https://doi.org/10.1111/ajt.16463

Organ Procurement and Transplantation Network (OPTN) [Internet]. Transplants by Donor Type. National Data; 2024. https://optn.transplant.hrsa.gov/data/view-data-reports/ national-data/

NHS Blood & Transplant. Kidney activity: Annual Report and Accounts 2024–2025 [Internet]. 2025 [cited 2025 Nov 23]. p 32. https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/36705/section-5-kidney-activity.pdf.

Haghighi AN, Ghobadi O, Najafizadeh K, Noohi F, Broumand B, Fazel I. 20 Years Iranian Experience of Organ Donation: Shifting From Compensated Living Unrelated Kidney Transplantation. Kidney Int Rep. 2025 Jan 29;10(4):979-982. https://doi.org/10.1016/j.ekir.2025.01.032

Saudi Center for Organ Transplantation (SCOT). Annual Report 2024 [Internet]. Riyadh: SCOT; 2024. https://www.scot.gov.sa/sites/default/files/???????%20??????%202024.pdf

Rizvi SA, Anwar Naqvi SA, Zafar MN, Hussain Z, Hashmi A, Akhtar F, et al. Pakistan abolishes kidney market and ushers in a new era of ethical transplantation. Int J Organ Transplant Med. 2010;1(4):193-7.

International Registry in Organ Donation and Transplantation (IRODaT). Pakistan – Database 2024. https://www.irodat.org/?p=database&c=PK&year=2024

Afzal A, Rauf MA, Khanum Z, Rahman HS, Rafique Z, Gulzar A, et al. Barriers to Renal Transplant in Pakistan. Cureus. 2025 May 26;17(5):e84850. https://doi.org/10.7759/cureus.84850

The Council of the International Islamic Fiqh Academy. A Human receiving the Organs of another Human, Dead or Alive (Organ Transplantation). Resolution No. 26 (1/4), 11 Feb 1988. https://iifa-aifi.org/en/32287.html. Accessed 2025 Nov 23

Additional Files

Published

20-05-2026

How to Cite

1.
Khalil MAM, Sadagah NM, Tan J, Hediki I, Anwar Ul Haque, Al-Qurashi SH. Deceased Donor Kidney Transplantation in Pakistan: An Underutilized Resource . J Saidu Med Coll [Internet]. 2026 May 20 [cited 2026 Nov. 10];16(2):226-8. Available from: http://jsmc.pk/index.php/jsmc/article/view/1461