INCIDENCE OF ADENOMYOSIS AND THEIR ASSOCIATIONS WITH OTHER UTERINE WALL PATHOLOGIES IN HYSTERECTOMY SPECIMENS

Abstract

BACKGROUND: Adenomyosis is a gynaecological condition in which there occurs an ectopic
endometrial tissue in myometrial layer of uterine wall. Adenomyosis is one of the most common causes
of abnormal uterine bleeding.
OBJECTIVE: To determine the incidence of adenomyosis and their association with other uterine
pathologies in hysterectomy specimens in northern district of Khyber pukhthunkhwa.
MATERIALS AND METHODS: This descriptive study was conducted in Gynecology department and
Pathology department of Saidu Medical College / Saidu teaching hospital Swat. The study period was
from June 2013 to June 2016. A total of 250 hysterectomies were included in the study. The inclusion
criteria was only hysterectomies specimens of any age, whereas exclusion criteria were autolysed
specimen. A minimum of two sections and a maximum of six sections were taken from the uterine wall.
Sections 5 micron thick were stained with H&E and reported by histopathologists. The data was
analysed in Statistical Package for Social Sciences (SPSS) version 16 for frequencies with percentages
and mean with standard deviation.
RESULTS: A total of 250 hysterectomies were included in this study with mean age of 37.5±8.47 years
and age range was from 25 to 65 years. The incidence of adenomyosis was 34.8% amongst 250
hysterectomies specimens and was the second common lesion where as leiomyoma was the first
common lesion. The most common age group in adenomyosis was between 35-45 years 43(49.42%)
cases followed by 25-35 years 32(36.78%) cases etc. Adenomyosis was present in 84(95.40%) cases
with endometrial wall thickness of more than 2.5 millimeter.
CONCLUSION: Adenomyosis was the second commonest lesion in hysterectomy specimen and was
significantly associated with other uterine pathologies.
KEY WORDS: Hysterectomy, Adenomyosis, Uterine wall thickness.