FREQUENCY OF HEPATITIS B AND HEPATITIS C IN MULTITRANSFUSED BETA THALASSAEMIA MAJOR PATIENTS IN DISTRICT SWAT
DOI:
https://doi.org/10.52206/jsmc.2013.3.2.299-302Abstract
BACKGROUND: Beta thalassaemia major is the commonest inherited as autosomal recessive disorder in
Pakistan. Almost all patients beta thalassaemia major require blood transfusion within the first two years of
life to prevent severe anaemia and its physical consequences. Due to repeated blood transfusions hepatitis B
and hepatitis C infections can occur in these patients. To document the prevalence and frequency of hepatitis
B & hepatitis C in multi transfused beta Thalassemia major patients in our set up.
STUDY DESIGN:Aprospective descriptive study.
PLACE AND DURATION OF STUDY: The study was conducted in thalassaemia care center A1 Fajar
Foundation Blood Transfusion ServicesSwat from 1-1-2012 to 31-12-2012.
PATIENTS AND METHODS: Study was carried on 170 multi transfused thalassaemia major patients
who were registered with A1 Fajar Foundation Swat, irrespective of age, sex, time of diagnosis. Only those
patients were included in the study who had received so far more than 10 transfusions. They were screened
for hepatitis B and C by Enzyme Linked Immunosorbent Assay (ELISA). The subjects were in the ages
range of 2-15 year,with 94 (55.29%) male and 76 (94:71%) female.
RESULTS: Out of these 10 patients (5.88%) were found to have hepatitis B surface antigen (HBsAg)
positive and 37 patients (21.76%) hepatitis C virus(HCV) antibody positive.
CONCLUSION: In spite of the fact that screened blood is used for transfusions, still a large number of
patients have been found infected with hepatitis B and C. It has been recommended that properly screened
bloods using a reliable and accurate method are used for screening of blood to prevent transfusion
transmitted diseases. It can be avoided by giving screened safe blood.
KEYWORDS: Hepatitis B, Hepatitis C,Thalassaemia Major,Transfusion
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2021 The authors retain the copyrights. Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website), as it can lead to productive exchanges, as well as greater citation of published work.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Readers may “Share-copy and redistribute the material in any medium or format” and “Adapt-remix, transform, and build upon the material”. The readers must give appropriate credit to the source of the material and indicate if changes were made to the material. Readers may not use the material for commercial purpose. The readers may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
