Comparison of efficacy of Amoxicillin versus Ceftriaxone in children with pneumonia
DOI:
https://doi.org/10.52206/jsmc.2017.7.2.%25pKeywords:
efficacy, Amoxicillin, Ceftriaxone, pneumoniaAbstract
BACKGROUND: Pneumonia is the leading cause of death in children worldwide. Pneumonia can be caused by viruses, bacteria 2 or fungi . Pneumonia can be prevented by immunization, adequate nutrition and by addressing environmental factors. Pneumonia 1 can be treated with antibiotics, but around 30% of children with pneumonia receive the antibiotics they need
OBJECTIVE: To compare the efficacy of injectable Amoxicillin vs Injection Ceftriaxone in children with pneumonia.
MATERIAL & METHODS: This study was conducted at a tertiary care hospital, Peshawar. Study design was randomized control 8 study in which the sample size was calculated on the bases of previous studies estimated efficacy of 89.9% of amoxycillin and 76.6% for injection Ceftriaxone, using standard error of proportion at 95% confidence intervals, with a margin of error of 80%, a sample size of 70 cases was selected for each group. More over non-probability consecutive sampling technique was used for sample collection. Patients were divided in two groups. Patients received Amoxicillin therapy was in Group A and patients received injection Ceftriaxone were in Group B. Patients were randomly and consecutively assigned to either group using lottery method.
RESULTS: Our results show that mean age in Group A was 2 years ± 2.23 and mean age in Group B was 2 years ± 2.47. In Group A 63% children were male and 37% children were female. Where as in Group B 65% children were male and 35% children were female. More over intravenous Amoxicillin (Group A) was effective in 78% children while intravenous Ceftriaxone was effective in 84% children.
CONCLUSION: Injection Ceftriaxone was more effective than injectable Amoxicillin in term of improvement of fever and respiratory rate in the treatment of pneumonia.
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