ASSESSMENT OF CONGENITAL MALFORMATIONS IN CONSANGUINEOUS MARRIAGES AMONG THE FAMILIES OF STUDENTS OF SAIDU MEDICAL COLLEGE SAIDU SHARIF.

Abstract

Consanguineous marriage is customary in many societies, which leads to an increased birth prevalence of
infants with severe recessive disorders (congenital malformations). All these disorders play a significant
role on world economy, productivity and become a huge burden on medical fraternity. Majority of these
disorders are preventable through proper “ Premarital consultation / counseling†of the male and female
before wedding for checking of “ Marital compatibility†.
Objective of this observational study is to assess the prevalence of congenital malformations in
consanguineous marriages among the families' of students of Saidu Medical College.
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Material & Methods:
Duration of study was 3 months.
Sample size Sampling Techniques: Stratified Randomized technique was used for selection of 100 houses/
families of students of the college, with equal strata taken from first to final year MBBS classes.
Result: From 504, 280(55.56%) of the children were from consanguineous marriages, while 224(44.45%)
were from non consanguineous marriages. From 25 cases with congenital anomalies, 23 (8.2%) cases were
from consanguineous marriages while only 2 (0.9 %) cases were from non- consanguineous marriages. Our
study shows that there is a significant correlation between parental marriages and the prevalence of
anomaly. 54 % couples out of 100 families were belonged to consanguineous marriages, of which 24 %,
17% and 13% marriages were belonged to 1 sl cousin, 2nd cousin and other cousins respectively. 46 % out of
100 families were belonged to non-consanguineous marriages.