Measuring Loss of Corneal Endothelial Cell Density and Retinal Nerve Fiber Layer Thickness in Primary Open Angle Glaucoma.

Authors

  • Bakht Samar Khan
  • Abid Nawaz
  • Imran Ahmad
  • Zaman Shah

DOI:

https://doi.org/10.52206/jsmc.2021.11.3.647

Abstract

Background: Primary open angle glaucoma is an irreversible disease causing a reduction in corneal endothelium cells mainly
responsible for corneal clarity along withnerve fiber layer loss.
ObjectiveiTo calculate loss of corneal endothelium density (CED) andretinalnerve fiber layer(RNFL) thickness in Primary open
angle glaucoma(POAG).
Material and Methods: It was a prospective observational study conducted in Khyber Teaching Hospital from April 2015 to
December 2019. A total of 112 patients were included in the study through consecutive non-probability sampling technique.
Patients were diagnosed with open angle glaucoma on the basis of intra ocular pressure (IOP), optic disc changes, visual fields
changes and Optical coherence tomography (OCT) findings. Corneal endothelium density and thickness of retinalnerve fiber layer
was calculated onthe basis of specular microscopy and OCT. These were compared with normalmatched values.
Results: The POAG patients have average 17.12% CED and 34.73% RNFLthickness loss.
Conclusion:It is observed that Corneal endothelial cell count may be evaluated along with nerve fiber layer thickness in Primary
open angle glaucoma.
Keywords.Specular microscopy, OCT, RNFL,POAG.

Author Biographies

Bakht Samar Khan

MTI, KTH, Peshawar.

Abid Nawaz

Kabir Medical College, Peshawar.

Imran Ahmad

Bach Khan Medical Complex, Mardan.

Zaman Shah

MTI, KTH, Peshawar.

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How to Cite

1.
Bakht Samar Khan, Abid Nawaz, Imran Ahmad, Zaman Shah. Measuring Loss of Corneal Endothelial Cell Density and Retinal Nerve Fiber Layer Thickness in Primary Open Angle Glaucoma. J Saidu Med Coll [Internet]. 2021 Nov. 20 [cited 2026 Nov. 10];11(3):137-41. Available from: http://jsmc.pk/index.php/jsmc/article/view/647

Issue

Vol. 11 No. 3 (2021): Journal of Saidu Medical College

Section

Original Article

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