FREQUENCY OF HBeAg POSITIVITY IN PATIENTS WITH HEPATITIS B INFECTION IN TEACHING HOSPITALS OF PESHAWAR
DOI:
https://doi.org/10.52206/jsmc.2013.3.2.368-372Abstract
OBJECTIVES: To determine the frequency of acute and chronic hepatitis HBeAg positivity in patients of
different ages and gender suffering from Hepatitis B Virus infection, and to rectify the key factors
responsible for its transmission.
METHODOLOGY: Cross sectional study conducted for duration of 3 months at tertiary care hospitals of
Peshawar on 220 patients suffering from hepatitis B infection that are screened for serum markers.non
probability convenient sampling technique was used and structured questionnaire was used as data
collection tool. Patient’s record was checked for serum markers. Data collected was analyzed by SPSS
version 16.
RESULTS: Out of total 220 cases with hepatitis B infection 145 were male while 75 were females.
103(46.8%) were found to be positive with raised level of serum marker HBeAg, predominantly more in
male gender and young age patients with mean age of 22 years. The serum level of (HBeAg) was high in
patients having chronic hepatitis as compare to acute hepatitis. Patients with positive HBeAg were
significantly associated with raised level ofALT.
CONCLUSIONS: The frequency of HBe Ag+ve in patients suffering from hepatitis B infection is 46.8%
with more predominant in young age patients associated with raised level ofALT.
RECOMMENDATIONS: Health education of the community regarding preventive measures from
hepatitis B infection and early diagnosis through mass screening program is recommended.
KEYWORDS: Serum marker HBeAg, acute hepatitis, chronic hepatitis, incubation period, ALT.
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