COMPARISON OF TOTAL LEUCOCYTE AND EOSINOPHIL COUNT IN MALE SMOKERS AND HEROIN ADDICTS IN PESHAWAR
DOI:
https://doi.org/10.52206/jsmc.2012.2.2.147-152Abstract
Background: The harmful components of tobacco smoke nicotine, tar and carbon monoxide affects
different haematological parameters. Heroin affects almost every system of the body including blood and its
components. The present study was conducted in Physiology department; Khyber Medical College
Peshawar from Jan 2006 to Dec 2007. The objective of the present study was to compare the affects of
cigarette smoking and heroin abuse on haematological parameters especially total leukocyte count and
eosinophil count.
Subject and Methods: The study was conducted on hundred age and sex matched subjects. The subjects
were divided into three groups i.e. forty cigarette smokers and forty heroin addicts and with twenty normal
(Control). Laboratory tests were performed at Pakistan Medical Research Council (P.M.R.C) Khyber
Medical College, Peshawar. Data was statistically analysed by computer using SPSS 10 software.
Results: Total leukocyte and eosinophil counts were raised in both cigarette smokers and heroin abusers as
compared to normal individuals. Total Leukocyte count (TLC) was found significantly higher (P<0.001) in
cigarette smokers as compared to heroin addicts whereas there was no statistically significant difference in
eosinophil count of cigarette smokers and heroin addicts. Neutrophil and lymphocyte percentages were
lower and monocyte percentage higher in both cigarette smokers and heroin addicts as compared to control
group.
Conclusion: Haematological parameters vary with cigarette smoking and heroin abuse. Therefore history of smoking
and heroin abuse should be considered while interpreting the investigation in such patients.
Key words: Leukocyte count, Eosinophil, Heroin addiction, Smoking.
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